![]() Thrombocytosis: A low MPV with a high platelet count suggests reactive thrombocytosis, which is common as inflammation, malignancy, and infection. As a result, blood clotting is quite difficult. Excessive bleeding is most common in thrombocytopenia patients due to low platelet count. Thrombocytopenia: Often a cause of low MPV, especially if it results from aplastic anemia, which interrupts platelet production. This suggests impaired production rather than greater destruction. HIV and AIDS: HIV-infected women have lower MPV than uninfected women. Lower MPV is expected in FMF patients when there is secondary thrombocytosis. Research shows that low MPV with platelet distribution width will help treat and diagnose bone marrow metastasis.įamilial Mediterranean fever (FMF): This is an autosomal recessive hereditary disease where there are frequent attacks of fever, arthritis, pleuritis, peritonitis, or erysipelas-like skin disease. ![]() For instance, low mean platelet volume has been observed in active lupus cases, rather than in people without a flare-up.Ĭertain cancers: Bone marrow cancer can cause a low mean platelet volume. MPV in the CBC is needed to diagnose appendicitis accurately.Īutoimmune disorders: Low MPV levels are often common in a number of autoimmune disorders. When stomachaches are due to appendicitis, there will likely be low MPV. Respiratory syncytial virus infection patients also often show a low MPV.Īppendicitis: Low MPV can help determine an acute appendicitis diagnosis. Viral infections: A respiratory viral infection is diagnosed through low mean platelet volume readings in a CBC. Rheumatoid arthritis: Low MPV levels have been reported in patients with active rheumatoid arthritis, but levels tend to also increase after treatment. Treatment for IBD will help increase MPV. Inflammatory bowel disease (IBD): Average platelet size decreases due to Crohnâs disease and ulcerative colitis. The following conditions have been known to result in abnormally low levels of MPV: There have not been conclusive tests to pinpoint one cause of low MPV readings. Even during the collection of blood samples, low MPV results have been discovered as the blood had clotted before the sample was tested. Low readings are seen in the early days of a womanâs menstrual cycle and in newborns. A low MPV count does increase the risk for serious blood loss if you are injured. It can be attributed to various disorders, diseases, injuries, drug reactions, and even natural hormone changes in the body. Low MPV: What Does It Mean?Ī low MPV result refers to a blood platelet count lower than normal. For instance, a post-partum MVP reading will register higher than normal. ![]() The volume levels can also change due to diseases and hormonal changes. Previous studies have shown a link between major depression and increased platelet activity. These number ranges are determined by a number of factors, one being the psychological state of the patient. With that, patients with a MPV between 9.7 fL and 12.8 fL are still deemed to be in a good range. As it is hard to imagine that minute of an amount, the normal MPV should range from 7.5 fL to 11.5 fL. One fL is equal to the metric unit of one quadrillionth of a liter. The volume of platelets is measured in femtoliters, or fL. We also tell you what to do when you have low MPV. In this article, you will learn everything about a low MPV range, including the causes and symptoms of low MPV. Your doctor will typically use the MPV test to decide whether further testing, such as a bone marrow biopsy, is needed. Having a low or high MPV may not be cause for concern alone it should be considered alongside the other CBC results, like platelet count. This reading determines if a patientâs body is producing larger than average platelets, indicative of platelet destruction or bone marrow diseases. The volume is determined by a machine, and a complete blood profile, known as a CBC (Complete Blood Count), is a blood test that checks for low MPV counts. The platelets are components of our blood responsible for stopping any bleeding by clumping and clotting blood vessel injuries. Mean platelet volume, or MPV, refers to the medical test reading of the size of the platelets in a blood sample. Disclaimer: Results are not guaranteed*** and may vary from person to person***.
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